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<p>[QUOTE="هدى, post: 35302, member: 607"]<p style="text-align: left">A change in the character of the regular cough of a smoker old male, particularly if it is associated with other new respiratory symptoms, should raise the possibility of </p><p>bronchogenic carcinoma<p style="text-align: left">.</p><p>I-Thoracic manifestations of Bronchogenic carcinoma</p><p><br /></p><p style="text-align: left">A- Bronchopulmonary presentations:</p> <p style="text-align: left">1- </p><p>Asymptomatic<p style="text-align: left"> (detected accidentally by routine x-ray as coin shadow)</p> <p style="text-align: left">2- </p><p>Cough <p style="text-align: left">and </p><p>haemoptysis<p style="text-align: left"> :</p> <p style="text-align: left"> Blood tinged sputum - Red current jelly i.e. sputum consist of Mucous, Tissue debris, RBCs</p> <p style="text-align: left"><br /></p> <p style="text-align: left">3- </p><p>Bronchial obstruction</p><p style="text-align: left">• Partial ==> Emphysema , Bronchiectasis</p> <p style="text-align: left">• Complete ==> Lung collapse</p> <p style="text-align: center">[ATTACH=full]103953[/ATTACH]</p><p><br /></p><p style="text-align: left">4- </p><p>Pneumonia<p style="text-align: left"> usually recurrent at the same site, or is slow to respond to treatment.</p> <p style="text-align: left"><br /></p> <p style="text-align: left">5- Lung</p><p>abscess<p style="text-align: left"> (due to secondary infection)</p> <p style="text-align: left">6- </p><p>Thoracic inlet syndrome<p style="text-align: left"> may occur due to bronchial carcinoma in the apex of the lung (superior sulcus tumour) causing invasion of :</p> <p style="text-align: left">• Upper 3 ribs</p> <p style="text-align: left">• Sympathetic chain ===> </p><p>Horner syndrome</p><p style="text-align: left"> - Ipsilateral partial ptosis.</p> <p style="text-align: left"> - Ipsilateral enophthalmos and a small pupil</p> <p style="text-align: left"> - Ipsilateral hypohidrosis of the face.</p> <p style="text-align: left">• SVC obstruction (congested non pulsating neck veins)</p> <p style="text-align: left">• Lower trunk of brachial plexus (Pancoast's syndrome) :</p> <p style="text-align: left">- Pain in shoulter and inner - Wasting of the smal1 muscles of the hand</p> <p style="text-align: left">• Subclavian artery ===> unequal pulse volume in both upper limbs .</p> <p style="text-align: left"><br /></p> <p style="text-align: left">7- Cor pulmonale due to lymphangitis carcinomatosa.</p> <p style="text-align: left"><br /></p> <p style="text-align: left">B - Pleural presentations:</p> <p style="text-align: left"><br /></p> <p style="text-align: left">*</p><p>Effusion<p style="text-align: left"> :</p> <p style="text-align: left">• Malignant effusion (</p><p>Exudate<p style="text-align: left">) : Massive ,Hemorrhagic, Rapidly re-accumulating</p> <p style="text-align: left"><br /></p> <p style="text-align: left">• </p><p>Transudate<p style="text-align: left"> : due to obstruction of azygos vein .</p> <p style="text-align: left">• </p><p>Chylous<p style="text-align: left"> : due to obstruction of the thoracic duct .</p> <p style="text-align: left">• </p><p>Empyema<p style="text-align: left"> : due to rupture of malignant abscess into pleura .</p> <p style="text-align: left"><br /></p> <p style="text-align: left">* </p><p>Dry pleurisy<p style="text-align: left"> may occur</p> <p style="text-align: left"><br /></p> <p style="text-align: left">C - </p><p>Mediastinal presentations<p style="text-align: left">:</p> <p style="text-align: left">Mediastinal spread may result in dysphagia .</p> <p style="text-align: left"><br /></p> <p style="text-align: left">• Hypercalcemia is usually caused by squamous cell carcinoma.</p> <p style="text-align: left">• Syndrome of inappropriate ADH and ectopic ACTH seretion are usually associated with small cell carcinoma.</p> <p style="text-align: left">• Clubbing most often with non small cell carcinoma.</p> <p style="text-align: left">• Gynecomastia is usually with large cell carcinoma.</p> <p style="text-align: left">• Hypertrophic pulmonary osteoarthropathy is usually with adenocarcinoma.</p> <p style="text-align: left">• Neurological syndromes may occur with any type of bronchial carcinoma.</p><p>II- Extra-thoracic manifestations of Bronchogenic carcinoma : </p><p><br /></p><p style="text-align: center"><br /></p> <p style="text-align: center"><br /></p><p>[/QUOTE]</p><p><br /></p>
[QUOTE="هدى, post: 35302, member: 607"][LEFT]A change in the character of the regular cough of a smoker old male, particularly if it is associated with other new respiratory symptoms, should raise the possibility of [/LEFT] bronchogenic carcinoma[LEFT].[/LEFT] I-Thoracic manifestations of Bronchogenic carcinoma [LEFT]A- Bronchopulmonary presentations: 1- [/LEFT] Asymptomatic[LEFT] (detected accidentally by routine x-ray as coin shadow) 2- [/LEFT] Cough [LEFT]and [/LEFT] haemoptysis[LEFT] : Blood tinged sputum - Red current jelly i.e. sputum consist of Mucous, Tissue debris, RBCs 3- [/LEFT] Bronchial obstruction [LEFT]• Partial ==> Emphysema , Bronchiectasis • Complete ==> Lung collapse[/LEFT] [CENTER][ATTACH=full]103953[/ATTACH][/CENTER] [LEFT]4- [/LEFT] Pneumonia[LEFT] usually recurrent at the same site, or is slow to respond to treatment. 5- Lung[/LEFT] abscess[LEFT] (due to secondary infection) 6- [/LEFT] Thoracic inlet syndrome[LEFT] may occur due to bronchial carcinoma in the apex of the lung (superior sulcus tumour) causing invasion of : • Upper 3 ribs • Sympathetic chain ===> [/LEFT] Horner syndrome [LEFT] - Ipsilateral partial ptosis. - Ipsilateral enophthalmos and a small pupil - Ipsilateral hypohidrosis of the face. • SVC obstruction (congested non pulsating neck veins) • Lower trunk of brachial plexus (Pancoast's syndrome) : - Pain in shoulter and inner - Wasting of the smal1 muscles of the hand • Subclavian artery ===> unequal pulse volume in both upper limbs . 7- Cor pulmonale due to lymphangitis carcinomatosa. B - Pleural presentations: *[/LEFT] Effusion[LEFT] : • Malignant effusion ([/LEFT] Exudate[LEFT]) : Massive ,Hemorrhagic, Rapidly re-accumulating • [/LEFT] Transudate[LEFT] : due to obstruction of azygos vein . • [/LEFT] Chylous[LEFT] : due to obstruction of the thoracic duct . • [/LEFT] Empyema[LEFT] : due to rupture of malignant abscess into pleura . * [/LEFT] Dry pleurisy[LEFT] may occur C - [/LEFT] Mediastinal presentations[LEFT]: Mediastinal spread may result in dysphagia . • Hypercalcemia is usually caused by squamous cell carcinoma. • Syndrome of inappropriate ADH and ectopic ACTH seretion are usually associated with small cell carcinoma. • Clubbing most often with non small cell carcinoma. • Gynecomastia is usually with large cell carcinoma. • Hypertrophic pulmonary osteoarthropathy is usually with adenocarcinoma. • Neurological syndromes may occur with any type of bronchial carcinoma.[/LEFT] II- Extra-thoracic manifestations of Bronchogenic carcinoma : [CENTER] [/CENTER][/QUOTE]
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Manifestations of Bronchogenic carcinoma
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